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Just minutes from Pearland, the Texas Medical Center (TMC)—the largest medical center in the world—offers 14 hospitals, 21 academic institutions, three medical schools and six nursing schools. TMC hospitals have been recognized by US News and World Report’s Annual Survey of America’s Hospitals in all 19 categories of adult care and all 10 pediatric care specialties. Some member institutions include:

  • Baylor Clinic
  • Memorial Hermann
  • Methodist
  • St. Luke’s Episcopal Hospital
  • Texas Children Hospital
  • MD Anderson Cancer Center


As Pearland’s population continues to grow, the community has seen a tremendous increase in hospital and other health care developments.

Hospital Corporation of America (HCA) operates HCA Healthcare Houston Pearland, a 97-bed, acute care hospital in Pearland. HCA Healthcare Houston Pearland is located at the southwest intersection of Highway 288 and County Road 2234 (Shadow Creek Parkway) on a 48-acre site that is currently home to a full-service, freestanding 24-hour emergency department, imaging center and a 3-story, 80,000 square-foot medical office building. HCA Houston Healthcare Pearland is a 144,000 square-foot, $71 million facility featuring surgical suites, medical/surgical beds, intensive care beds, an emergency department, and an imaging department that will include magnetic resonance imaging (MRI), computerized tomography (CT), catheterization lab, echocardiogram testing, and nuclear medicine modalities.

Memorial Hermann‘s medical campus in Pearland includes a 4-story, 64-bed acute care hospital that features an intensive care unit, operating rooms, cardiac catheterization labs, medical/surgical units, women’s and neonatology services. The multi-purpose complex is located on a 40-acre site that is also home to an outpatient imaging center, diagnostic lab services, and two medical office building. In September 2022, Memorial Hermann announced a new $18.4 million expansion project that will build out a second-floor shell space to add 33 beds. It will also include adding two intensive care unit (ICU) beds and relocating 10 ICU beds to the second floor. The current ICU space on the fourth floor will become a new Intermediate Care Unit (IMU). The expansion will also include an additional 21 universal beds, bringing the total number of beds in the hospital to 97.

Encompass Health operates a 40-bed rehabilitation hospital on Business Center Drive.

Houston Methodist Primary Care Group operates Pearland Medical Commons, a 46,000 square foot primary care practice on FM 518 near Cullen.  The medical office building is occupied by Methodist physicians, offering primary care and orthopedic and sports medicine services.

Kelsey-Seybold operates a 55,000 square-foot multi specialty clinic on State Highway 288 and Business Center Drive. In 2023, Kelsey-Seybold Clinic completed construction on a 27,000-square-foot expansion of its Pearland Clinic. As part of the expansion, Kelsey-Seybold Clinic – Pearland has capacity for an additional 17 providers, bringing the total provider count to 44. The expansion adds Otolaryngology, Optometry, Ophthalmology, Surgery, and Urology services. Pearland Clinic expansion also adds new rotations in Dermatology, OB/GYN, Family Medicine, Internal Medicine, Allergy, Pediatrics, Endocrinology, Neurology, Orthopedics, Rheumatology, and Spine. Kelsey-Seybold Clinic – Pearland also expanded its ancillary services, making room for an additional X-ray machine. The expansion added space to the pharmacy and a new pharmacy drive through for greater convenience.

Texas Children’s Hospital opened its first ever combined Pediatrics and OB/GYN center on Broadway.